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- In especially severe cases, patients are shown a single-group blood transfusion in order to replace respiratory enzymes, as well as giving oxygen. The use of an artificial pancreas can also be an important help in helping these patients.
- Patients who have undergone hypoglycemic coma are recommended to use drugs that stimulate metabolic processes in the brain: nootropics (glutamic acid, piracetam, encephabol, nootrolil, aminolone, etc.), drugs that selectively dilate cerebral vessels (stugeron, cinnarizine) or combined drugs ( phases, nooses) within 3-4 weeks.
Without medical assistance, patients in a state of hypoglycemic coma usually die, although in clinical practicecases of spontaneous exit from this state within a few hours.
In clinical practice, it is advisable to distinguish between acute and chronic insulin resistance. Levitra includes those cases when the patient's need for insulin increases rapidly and then decreases within 1-2 days. As a rule, diabetic ketoacidosis is combined with it. The chronic form is observed in patients with diabetes for several months, and sometimes years. It develops most often after several years from the start of insulin therapy.
According to the classification proposed by Burson and Yalov, insulin resistance is divided into mild, moderate and severe. With a mild degree, the daily requirement for insulin is 80-125 IU, with an average degree - 125-200 IU, and with a severe degree - more than 200 IU. The literature describes cases of severe insulin resistance, when the required dose of Levitra pills per day reached 50,000 IU. Severe insulin resistance is often observed in patients with lipoatrophic diabetes.
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Treatment of insulin resistance is sometimes a difficult task. Strict adherence to the dietary regimen, rational physical activity, rehabilitation of foci of infection, treatment of concomitant diseases, prevention of stressful situations are important points in its solution.
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Increasing the dose of insulin up to the development of hypoglycemia, especially against the background of intravenous administration of the drug, often leads to an increase in the sensitivity of peripheral tissues to it and overcoming insulin resistance.
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Changing the type of drug, in particular to monopeak, and especially human, helps to eliminate this complication.
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With insulin resistance caused by an increase in the concentration of antibodies to insulin in the blood, glucocorticoids, which suppress the antigen-antibody reaction, are widely used.
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In this case, the appointment of prednisolone at a dose of 30-40 mg per day daily or every other day with a gradual decrease in dose over 1-2 months may have a positive effect.